The Three Macular Carotenoids: Complementary Functions of Lutein, Zeaxanthin and Meso-Zeaxanthin

JAMES STRINGHAM

Lutein and the two zeaxanthin isomers, RR-zeaxanthin (3R,3’R-zeaxanthin) and meso-zeaxanthin (3R,3’S-RS-zeaxanthin) are the only three carotenoids found in the eye, specifically in the macula of the retina (Bone et al. 1997). RR-zeaxanthin and meso-zeaxanthin are both considered zeaxanthin; they differ only in the spatial orientation of the hydroxyl group on the C3’ chiral position (Nolan et al. 2013 – see… More →

Thank You for Your Support During AMD Awareness Month!

Thank You For Your Support Chalk Illustration

MacuHealth would like to extend a sincere thank you to everyone who shared content, used the campaign hashtags and discussed age-related macular degeneration in any way, shape or form during February. (AMD Awareness month) An additional special thank you goes to all of the doctors, technicians and receptionists who displayed and promoted AMD educational materials within their practices. It is so important for patients… More →

Is Alzheimer’s Disease Related to Macular Pigment Levels?

The Journal of Alzeheimer’s Disease recently published a study that investigated the incidence of macular disease among subjects with moderate alzheimer’s disease. The July 2014 study looked to determine whether there is a significant the correlation between low macular pigment levels and the neurological condition. The study was comprised of 36 patients with early alzheimer’s disease and 33 control subjects… More →

Supplementation with Three Different Macular Carotenoid Formulations in Patients with Early AMD

stephen beatty

A recent study published by the Journal of Retina researched the effects of three different macular carotenoid formulations in patients with early age-related macular degeneration. The 36 month study is the longest of its kind and was comprised of 52 subjects who all suffer from early AMD. By using three different carotenoid formulations (one being mostly lutein, another being the… More →

Supplementation and AMD: The Results of AREDS-2

Back in 2001, researchers involved in the original AREDS (age-related eye disease study) reported that a formulation of vitamin c, vitamin e, beta-carotene, zinc and copper could reduce one’s risk of developing age-related macular degeneration. However, this formula received a few criticisms- primarily regarding its inclusion of potentially harmful beta-carotene. In fact, during the original AREDS trial, the National Cancer… More →